Lineage for d2cnea2 (2cne A:2-281)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2454571Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 2454572Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 2454684Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (7 protein domains)
    has an extension to the beta-sheet of 3 antiparallel strands before strand 4
  6. 2454892Protein automated matches [190252] (3 species)
    not a true protein
  7. 2454893Species Human (Homo sapiens) [TaxId:9606] [187034] (34 PDB entries)
  8. 2454906Domain d2cnea2: 2cne A:2-281 [130640]
    Other proteins in same PDB: d2cnea3
    automated match to d1bzja_
    complexed with bog, dfj, so4

Details for d2cnea2

PDB Entry: 2cne (more details), 1.8 Å

PDB Description: structural insights into the design of nonpeptidic isothiazolidinone- containing inhibitors of protein tyrosine phosphatase 1b
PDB Compounds: (A:) tyrosine-protein phosphatase non-receptor type 1

SCOPe Domain Sequences for d2cnea2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2cnea2 c.45.1.2 (A:2-281) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2cnea2:

Click to download the PDB-style file with coordinates for d2cnea2.
(The format of our PDB-style files is described here.)

Timeline for d2cnea2:

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