SCOPe 2.08: Domain d2cloa_: 2clo A:

Lineage for d2cloa_ (2clo A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (7 families)

5. Family c.1.2.4: Tryptophan biosynthesis enzymes [51381] (4 proteins)

6. Protein automated matches [190053] (10 species)
   not a true protein

7. Species Salmonella typhimurium [TaxId:90371] [189632] (10 PDB entries)

8. Domain d2cloa_: 2clo A: [130584]
   Other proteins in same PDB: d2clob_
   automated match to d1a5aa_
   complexed with f19, na, pls

Details for d2cloa_

PDB Entry: 2clo, 1.5 Å

PDB Description: tryptophan synthase (external aldimine state) in complex with (naphthalene-2'-sulfonyl)-2-amino-1-ethylphosphate (f19)

PDB Compounds: (A:) tryptophan synthase alpha chain

SCOPe Domain Sequences for d2cloa_:

Sequence, based on SEQRES records:

>d2cloa_ c.1.2.4 (A:) automated matches {Salmonella typhimurium [TaxId: 90371]}
eryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdpladg
ptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceqv
gvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllsrsg
vtgaenrgalplhhlieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivkii
eknlaspkqmlaelrsfvsamkaasra

Sequence, based on observed residues (ATOM records):

>d2cloa_ c.1.2.4 (A:) automated matches {Salmonella typhimurium [TaxId: 90371]}
eryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdpladg
ptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceqv
gvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllsrsg
vtghhlieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivkiieknlaspkq
mlaelrsfvsamkaasra

Timeline for d2cloa_:

• d2cloa_ first appeared in SCOP 1.73, called d2cloa1
  
• d2cloa_ appears in SCOPe 2.07