Lineage for d2cjmc_ (2cjm C:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2542927Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 2542928Species Human (Homo sapiens) [TaxId:9606] [88856] (379 PDB entries)
    Uniprot P24941
  8. 2543207Domain d2cjmc_: 2cjm C: [130544]
    Other proteins in same PDB: d2cjmb1, d2cjmb2, d2cjmd1, d2cjmd2
    automated match to d1aq1__
    complexed with atp, mg

Details for d2cjmc_

PDB Entry: 2cjm (more details), 2.3 Å

PDB Description: Mechanism of CDK inhibition by active site phosphorylation: CDK2 Y15p T160p in complex with cyclin A structure
PDB Compounds: (C:) Cell division protein kinase 2

SCOPe Domain Sequences for d2cjmc_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2cjmc_ d.144.1.7 (C:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlr

SCOPe Domain Coordinates for d2cjmc_:

Click to download the PDB-style file with coordinates for d2cjmc_.
(The format of our PDB-style files is described here.)

Timeline for d2cjmc_: