Lineage for d2cija3 (2cij A:57-117,A:351-593)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2495627Fold c.56: Phosphorylase/hydrolase-like [53162] (8 superfamilies)
    core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops
  4. 2497307Superfamily c.56.5: Zn-dependent exopeptidases [53187] (10 families) (S)
    core: mixed beta-sheet of 8 strands, order 12435867; strands 2, 6 & 7 are antiparallel to the rest
  5. 2497673Family c.56.5.5: FolH catalytic domain-like [53210] (2 proteins)
  6. 2497674Protein Glutamate carboxypeptidase II FOLH1 [142522] (1 species)
    Folate hydrolase 1, FolH homologue
  7. 2497675Species Human (Homo sapiens) [TaxId:9606] [142523] (34 PDB entries)
    Uniprot Q04609 57-117,351-593
  8. 2497705Domain d2cija3: 2cij A:57-117,A:351-593 [130495]
    Other proteins in same PDB: d2cija1, d2cija2
    automated match to d2c6ca3
    complexed with ca, cl, met, nag, zn

Details for d2cija3

PDB Entry: 2cij (more details), 2.4 Å

PDB Description: membrane-bound glutamate carboxypeptidase ii (gcpii) with bound methionine
PDB Compounds: (A:) glutamate carboxypeptidase II

SCOPe Domain Sequences for d2cija3:

Sequence, based on SEQRES records: (download)

>d2cija3 c.56.5.5 (A:57-117,A:351-593) Glutamate carboxypeptidase II FOLH1 {Human (Homo sapiens) [TaxId: 9606]}
nmkafldelkaenikkflynftqiphlagteqnfqlakqiqsqwkefgldsvelahydvl
lXevtriynvigtlrgavepdryvilgghrdswvfggidpqsgaavvheivrsfgtlkke
gwrprrtilfaswdaeefgllgstewaeensrllqergvayinadssiegnytlrvdctp
lmyslvhnltkelkspdegfegkslyeswtkkspspefsgmprisklgsgndfevffqrl
giasgrarytknwetnkfsgyplyhsvyetyelvekfydpmfkyhltvaqvrggmvfela
nsivl

Sequence, based on observed residues (ATOM records): (download)

>d2cija3 c.56.5.5 (A:57-117,A:351-593) Glutamate carboxypeptidase II FOLH1 {Human (Homo sapiens) [TaxId: 9606]}
nmkafldelkaenikkflynftqiphlagteqnfqlakqiqsqwkefgldsvelahydvl
lXevtriynvigtlrgavepdryvilgghrdswvfggidpqsgaavvheivrsfgtlkke
gwrprrtilfaswdaeefgllgstewaeensrllqergvayinadssiegnytlrvdctp
lmyslvhnltkelkspdegfegkslyeswtkkspspefsgmprisklgsgndfevffqrl
giasgrarytknfsgyplyhsvyetyelvekfydpmfkyhltvaqvrggmvfelansivl

SCOPe Domain Coordinates for d2cija3:

Click to download the PDB-style file with coordinates for d2cija3.
(The format of our PDB-style files is described here.)

Timeline for d2cija3: