SCOPe 2.07: Domain d2cija2: 2cij A:118-350

Lineage for d2cija2 (2cij A:118-350)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.8: The "swivelling" beta/beta/alpha domain [52008] (10 superfamilies)
   3 layers: b/b/a; the central sheet is parallel, and the other one is antiparallel; there are some variations in topology
   this domain is thought to be mobile in most multi-domain proteins known to contain it

4. Superfamily c.8.4: PA domain [52025] (1 family)

5. Family c.8.4.1: PA domain [52026] (2 proteins)

6. Protein Glutamate carboxypeptidase II [141984] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [141985] (34 PDB entries)
   Uniprot Q04609 118-350

8. Domain d2cija2: 2cij A:118-350 [130494]
   Other proteins in same PDB: d2cija1, d2cija3
   automated match to d2c6ca2
   complexed with ca, cl, met, nag, zn

Details for d2cija2

PDB Entry: 2cij, 2.4 Å

PDB Description: membrane-bound glutamate carboxypeptidase ii (gcpii) with bound methionine

PDB Compounds: (A:) glutamate carboxypeptidase II

SCOPe Domain Sequences for d2cija2:

Sequence, based on SEQRES records:

>d2cija2 c.8.4.1 (A:118-350) Glutamate carboxypeptidase II {Human (Homo sapiens) [TaxId: 9606]}
sypnkthpnyisiinedgneifntslfeppppgyenvsdivppfsafspqgmpegdlvyv
nyartedffklerdmkincsgkiviarygkvfrgnkvknaqlagakgvilysdpadyfap
gvksypdgwnlpgggvqrgnilnlngagdpltpgypaneyayrrgiaeavglpsipvhpi
gyydaqkllekmggsappdsswrgslkvpynvgpgftgnfstqkvkmhihstn

Sequence, based on observed residues (ATOM records):

>d2cija2 c.8.4.1 (A:118-350) Glutamate carboxypeptidase II {Human (Homo sapiens) [TaxId: 9606]}
sypnkthpnyisiinedgneifntslfeppppgyenvsdivppfsafspqgmpegdlvyv
nyartedffklerdmkincsgkiviarygkvfrgnkvknaqlagakgvilysdpadyfap
gvksypdgwnlpgggvqrgnilnlngagdpltpgypaneyayrrgiaeavglpsipvhpi
gyydaqkllekmggsappdsswrgslkvpynvgpgftfstqkvkmhihstn

Timeline for d2cija2:

• d2cija2 first appeared in SCOP 1.73
  
• d2cija2 appears in SCOPe 2.06
  
• d2cija2 appears in the current release, SCOPe 2.08