Lineage for d2cemb_ (2cem B:)

  1. Root: SCOPe 2.08
  2. Class b: All beta proteins [48724] (180 folds)
  3. Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. Protein Human immunodeficiency virus type 1 protease [50632] (9 species)
  7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (578 PDB entries)
    Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167
  8. Domain d2cemb_: 2cem B: [130349]
    automated match to d1ajva_
    complexed with 2ah

Details for d2cemb_

PDB Entry: 2cem (more details), 1.8 Å

PDB Description: p1' extended hiv-1 protease inhibitors encompassing a tertiary alcohol in the transition-state mimicking scaffold
PDB Compounds: (B:) pol protein

SCOPe Domain Sequences for d2cemb_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2cemb_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

SCOPe Domain Coordinates for d2cemb_ are not available.

Timeline for d2cemb_:

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Domains from other chains:
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d2cema_