SCOPe 2.06: Domain d2ccsa_: 2ccs A:

Lineage for d2ccsa_ (2ccs A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families)

5. Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain [55875] (2 proteins)

6. Protein automated matches [190229] (11 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187292] (141 PDB entries)

8. Domain d2ccsa_: 2ccs A: [130255]
   automated match to d1osfa_
   complexed with 4bh

Details for d2ccsa_

PDB Entry: 2ccs, 1.79 Å

PDB Description: human hsp90 with 4-chloro-6-(4-piperazin-1-yl-1h-pyrazol-3-yl)- benzene-1,2-diol

PDB Compounds: (A:) heat shock protein hsp-90 alpha

SCOPe Domain Sequences for d2ccsa_:

Sequence; same for both SEQRES and ATOM records:

>d2ccsa_ d.122.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
evetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryetltdpskldsgke
lhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadismigqfg
vgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedqt
eyleerrikeivkkhsqfigypitlfvek

Timeline for d2ccsa_:

• d2ccsa_ first appeared in SCOP 1.73, called d2ccsa1
  
• d2ccsa_ appears in SCOPe 2.05
  
• d2ccsa_ appears in SCOPe 2.07
  
• d2ccsa_ appears in the current release, SCOPe 2.08