Lineage for d2c6tc1 (2c6t C:1-296)

  1. Root: SCOP 1.73
  2. 713694Class d: Alpha and beta proteins (a+b) [53931] (334 folds)
  3. 734668Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 734669Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 734710Family d.144.1.7: Protein kinases, catalytic subunit [88854] (61 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 734916Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 734926Species Human (Homo sapiens) [TaxId:9606] [88856] (124 PDB entries)
  8. 735058Domain d2c6tc1: 2c6t C:1-296 [130007]
    Other proteins in same PDB: d2c6tb1, d2c6tb2, d2c6td1, d2c6td2
    automatically matched to d1vywa_
    complexed with dt5

Details for d2c6tc1

PDB Entry: 2c6t (more details), 2.61 Å

PDB Description: crystal structure of the human cdk2 complexed with the triazolopyrimidine inhibitor
PDB Compounds: (C:) Cell division protein kinase 2

SCOP Domain Sequences for d2c6tc1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2c6tc1 d.144.1.7 (C:1-296) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl

SCOP Domain Coordinates for d2c6tc1:

Click to download the PDB-style file with coordinates for d2c6tc1.
(The format of our PDB-style files is described here.)

Timeline for d2c6tc1: