Lineage for d2c6ta_ (2c6t A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 protein domains)
    members organized in the groups and subfamiles specified by the comments
  6. 2542927Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 2542928Species Human (Homo sapiens) [TaxId:9606] [88856] (378 PDB entries)
    Uniprot P24941
  8. 2543299Domain d2c6ta_: 2c6t A: [130004]
    Other proteins in same PDB: d2c6tb1, d2c6tb2, d2c6td1, d2c6td2
    automated match to d1aq1__
    complexed with dt5

Details for d2c6ta_

PDB Entry: 2c6t (more details), 2.61 Å

PDB Description: crystal structure of the human cdk2 complexed with the triazolopyrimidine inhibitor
PDB Compounds: (A:) Cell division protein kinase 2

SCOPe Domain Sequences for d2c6ta_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2c6ta_ d.144.1.7 (A:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl

SCOPe Domain Coordinates for d2c6ta_:

Click to download the PDB-style file with coordinates for d2c6ta_.
(The format of our PDB-style files is described here.)

Timeline for d2c6ta_: