SCOP 1.73: Domain d2c6oa1: 2c6o A:1-297

Lineage for d2c6oa1 (2c6o A:1-297)

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (61 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
   CMGC group; CDKs subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [88856] (124 PDB entries)

8. Domain d2c6oa1: 2c6o A:1-297 [130000]
   automatically matched to d1vywa_
   complexed with 4sp

Details for d2c6oa1

PDB Entry: 2c6o, 2.1 Å

PDB Description: crystal structure of the human cdk2 complexed with the triazolopyrimidine inhibitor

PDB Compounds: (A:) Cell division protein kinase 2

SCOP Domain Sequences for d2c6oa1:

Sequence, based on SEQRES records:

>d2c6oa1 d.144.1.7 (A:1-297) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlr

Sequence, based on observed residues (ATOM records):

>d2c6oa1 d.144.1.7 (A:1-297) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirlvpstaireisllkelnhpnivkl
ldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhr
dlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystavdi
wslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarq
dfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlr

Timeline for d2c6oa1:

• d2c6oa1 is new in SCOP 1.73
  
• d2c6oa1 appears in SCOP 1.75
  
• d2c6oa1 appears in the current release, SCOPe 2.08, called d2c6oa_