Lineage for d2c5xb2 (2c5x B:310-432)

  1. Root: SCOPe 2.08
  2. Class a: All alpha proteins [46456] (290 folds)
  3. Fold a.74: Cyclin-like [47953] (1 superfamily)
    core: 5 helices; one helix is surrounded by the others
  4. Superfamily a.74.1: Cyclin-like [47954] (4 families) (S)
    duplication: consists of two domains of this fold
  5. Family a.74.1.1: Cyclin [47955] (9 proteins)
  6. Protein Cyclin A [47956] (2 species)
  7. Species Human (Homo sapiens) [TaxId:9606] [47957] (88 PDB entries)
    Uniprot P20248 175-432
  8. Domain d2c5xb2: 2c5x B:310-432 [129961]
    Other proteins in same PDB: d2c5xa_, d2c5xc_
    automated match to d1h27b2
    complexed with mtw

Details for d2c5xb2

PDB Entry: 2c5x (more details), 2.9 Å

PDB Description: differential binding of inhibitors to active and inactive cdk2 provides insights for drug design
PDB Compounds: (B:) cyclin a2

SCOPe Domain Sequences for d2c5xb2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2c5xb2 a.74.1.1 (B:310-432) Cyclin A {Human (Homo sapiens) [TaxId: 9606]}
tvnqfltqyflhqqpanckveslamflgelslidadpylkylpsviagaafhlalytvtg
qswpeslirktgytleslkpclmdlhqtylkapqhaqqsirekyknskyhgvsllnppet
lnl

SCOPe Domain Coordinates for d2c5xb2 are not available.

Timeline for d2c5xb2:

View in 3D
Domains from same chain:
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d2c5xb1
View in 3D
Domains from other chains:
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d2c5xa_, d2c5xc_, d2c5xd1, d2c5xd2