Lineage for d2c5vd1 (2c5v D:175-309)

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2718075Fold a.74: Cyclin-like [47953] (1 superfamily)
    core: 5 helices; one helix is surrounded by the others
  4. 2718076Superfamily a.74.1: Cyclin-like [47954] (4 families) (S)
    duplication: consists of two domains of this fold
  5. 2718077Family a.74.1.1: Cyclin [47955] (9 proteins)
  6. 2718090Protein Cyclin A [47956] (2 species)
  7. 2718126Species Human (Homo sapiens) [TaxId:9606] [47957] (89 PDB entries)
    Uniprot P20248 175-432
  8. 2718455Domain d2c5vd1: 2c5v D:175-309 [129956]
    Other proteins in same PDB: d2c5va_, d2c5vc_
    automated match to d1h27b1
    complexed with ck4

Details for d2c5vd1

PDB Entry: 2c5v (more details), 2.9 Å

PDB Description: differential binding of inhibitors to active and inactive cdk2 provides insights for drug design
PDB Compounds: (D:) cyclin a2

SCOPe Domain Sequences for d2c5vd1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2c5vd1 a.74.1.1 (D:175-309) Cyclin A {Human (Homo sapiens) [TaxId: 9606]}
vpdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqnetlhl
avnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkqvlrm
ehlvlkvltfdlaap

SCOPe Domain Coordinates for d2c5vd1:

Click to download the PDB-style file with coordinates for d2c5vd1.
(The format of our PDB-style files is described here.)

Timeline for d2c5vd1: