SCOP 1.75: Domain d2c5ld1: 2c5l D:2134-2238

Lineage for d2c5ld1 (2c5l D:2134-2238)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.15: beta-Grasp (ubiquitin-like) [54235] (14 superfamilies)
   core: beta(2)-alpha-beta(2); mixed beta-sheet 2143

4. Superfamily d.15.1: Ubiquitin-like [54236] (8 families)

5. Family d.15.1.5: Ras-binding domain, RBD [54263] (13 proteins)
   contains Pfam PF00788 and Pfam PF02196

6. Protein Phospholipase C-epsilon-1 [142966] (1 species)
   contains several Ras-binding domains; some are 'hidden' in the sequence

7. Species Human (Homo sapiens) [TaxId:9606] [142967] (3 PDB entries)
   Uniprot Q9P212 2006-2114! Uniprot Q9P212 2131-2246! Uniprot Q9P212 2134-2239

8. Domain d2c5ld1: 2c5l D:2134-2238 [129925]
   Other proteins in same PDB: d2c5la1, d2c5lb1
   automatically matched to 2C5L C:2134-2239
   complexed with gol, gtp, mg; mutant

Details for d2c5ld1

PDB Entry: 2c5l, 1.9 Å

PDB Description: structure of plc epsilon ras association domain with hras

PDB Compounds: (D:) phosphoinositide-specific phospholipase c plc-epsilon

SCOP Domain Sequences for d2c5ld1:

Sequence, based on SEQRES records:

>d2c5ld1 d.15.1.5 (D:2134-2238) Phospholipase C-epsilon-1 {Human (Homo sapiens) [TaxId: 9606]}
eesffvqvhdvspeqprtvikaprvstaqdviqqtlckakyslsilsnpnpsdyvlleev
vkdttnkktttpkssqrvlldqecvfqaqskwkgagkfilklkeq

Sequence, based on observed residues (ATOM records):

>d2c5ld1 d.15.1.5 (D:2134-2238) Phospholipase C-epsilon-1 {Human (Homo sapiens) [TaxId: 9606]}
eesffvqvhdvspeqprtvikaprvstaqdviqqtlckakyslsilsnpnpsdyvlleev
sqrvlldqecvfkfilklkeq

Timeline for d2c5ld1:

• d2c5ld1 first appeared in SCOP 1.73
  
• d2c5ld1 is called d2c5ld_ in SCOPe 2.01
  
• d2c5ld1 appears in the current release, SCOPe 2.08, called d2c5ld_