SCOPe 2.08: Domain d2c4gc2: 2c4g C:1-298

Lineage for d2c4gc2 (2c4g C:1-298)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d2c4gc2: 2c4g C:1-298 [129812]
   Other proteins in same PDB: d2c4ga3, d2c4gb1, d2c4gb2, d2c4gc3, d2c4gd1, d2c4gd2
   automated match to d1vywa_
   complexed with 514, so4

Details for d2c4gc2

PDB Entry: 2c4g, 2.7 Å

PDB Description: structure of cdk2-cyclin a with pha-533514

PDB Compounds: (C:) Cell division protein kinase 2

SCOPe Domain Sequences for d2c4gc2:

Sequence; same for both SEQRES and ATOM records:

>d2c4gc2 d.144.1.7 (C:1-298) automated matches {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Timeline for d2c4gc2:

• d2c4gc2 first appeared in SCOP 1.73, called d2c4gc1
  
• d2c4gc2 appears in SCOPe 2.07