Lineage for d2c3ka_ (2c3k A:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2220941Protein automated matches [190091] (17 species)
    not a true protein
  7. 2221040Species Human (Homo sapiens) [TaxId:9606] [188447] (653 PDB entries)
  8. 2221636Domain d2c3ka_: 2c3k A: [129738]
    automated match to d3nlba_
    complexed with abo

Details for d2c3ka_

PDB Entry: 2c3k (more details), 2.6 Å

PDB Description: identification of a buried pocket for potent and selective inhibition of chk1: prediction and verification
PDB Compounds: (A:) Serine/threonine-protein kinase Chk1

SCOPe Domain Sequences for d2c3ka_:

Sequence, based on SEQRES records: (download)

>d2c3ka_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicinkmlnhe
nvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgig
ithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefh
aepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhki
lvenpsaritipdikkdrwynkplk

Sequence, based on observed residues (ATOM records): (download)

>d2c3ka_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vedwdlvqtlgegaygevqlavnrvteeavavkivdmkrcpenikkeicinkmlnhenvv
kfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigith
rdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaep
vdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilve
npsaritipdikkdrwynkplk

SCOPe Domain Coordinates for d2c3ka_:

Click to download the PDB-style file with coordinates for d2c3ka_.
(The format of our PDB-style files is described here.)

Timeline for d2c3ka_: