SCOPe 2.01: Domain d2c2wc2: 2c2w C:8-192

Lineage for d2c2wc2 (2c2w C:8-192)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.132: Bacterial fluorinating enzyme, N-terminal domain [102521] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 6 strands; order: 213546, strand 5 is antiparallel to the rest; topological similarity to the MogA-like family fold

4. Superfamily c.132.1: Bacterial fluorinating enzyme, N-terminal domain [102522] (1 family)

5. Family c.132.1.1: Bacterial fluorinating enzyme, N-terminal domain [102523] (1 protein)

6. Protein 5'-fluoro-5'-deoxyadenosine synthase [102524] (1 species)

7. Species Streptomyces cattleya [TaxId:29303] [102525] (14 PDB entries)

8. Domain d2c2wc2: 2c2w C:8-192 [129703]
   Other proteins in same PDB: d2c2wa1, d2c2wb1, d2c2wc1
   automatically matched to d1rqpa2
   complexed with 5cd, cl

Details for d2c2wc2

PDB Entry: 2c2w, 2 Å

PDB Description: the fluorinase from streptomyces cattleya is also a chlorinase. structure of 5'-chloro-5'-deoxyadenosine crystallised in the fluorinase.

PDB Compounds: (C:) 5'-fluoro-5'-deoxyadenosine synthase

SCOPe Domain Sequences for d2c2wc2:

Sequence; same for both SEQRES and ATOM records:

>d2c2wc2 c.132.1.1 (C:8-192) 5'-fluoro-5'-deoxyadenosine synthase {Streptomyces cattleya [TaxId: 29303]}
rpiiafmsdlgttddsvaqckglmysicpdvtvvdvchsmtpwdveegaryivdlprffp
egtvfatttypatgtttrsvavrikqaakggargqwagsgagferaegsyiyiapnngll
ttvleehgyleayevtspkvipeqpeptfysremvaipsahlaagfplsevgrpledhei
vrfnr

Timeline for d2c2wc2:

• d2c2wc2 first appeared in SCOP 1.73
  
• d2c2wc2 appears in SCOP 1.75
  
• d2c2wc2 appears in SCOPe 2.02
  
• d2c2wc2 appears in the current release, SCOPe 2.08