SCOPe 2.08: Domain d2c2ha1: 2c2h A:3-177

Lineage for d2c2ha1 (2c2h A:3-177)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (81 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Rac3 [142255] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [142256] (1 PDB entry)
   Uniprot P60763 3-177

8. Domain d2c2ha1: 2c2h A:3-177 [129668]
   Other proteins in same PDB: d2c2hb_
   complexed with ca, gdp, mg, so4

Details for d2c2ha1

PDB Entry: 2c2h, 1.85 Å

PDB Description: crystal structure of the human rac3 in complex with gdp

PDB Compounds: (A:) ras-related c3 botulinum toxin substrate 3

SCOPe Domain Sequences for d2c2ha1:

Sequence, based on SEQRES records:

>d2c2ha1 c.37.1.8 (A:3-177) Rac3 {Human (Homo sapiens) [TaxId: 9606]}
aikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtagqe
dydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcphtpillvgtkldlrdd
kdtierlrdkklapitypqglamareigsvkylecsaltqrglktvfdeairavl

Sequence, based on observed residues (ATOM records):

>d2c2ha1 c.37.1.8 (A:3-177) Rac3 {Human (Homo sapiens) [TaxId: 9606]}
aikcvvvgdgavgktcllisyttnafpgdnysanvmvdgkpvnlglwdtagqedydrlrp
lsypqtdvflicfslvspasfenvrakwypevrhhcphtpillvgtkldlrddkdtierl
rdkklapitypqglamareigsvkylecsaltqrglktvfdeairavl

Timeline for d2c2ha1:

• d2c2ha1 first appeared in SCOP 1.73
  
• d2c2ha1 appears in SCOPe 2.07