SCOPe 2.06: Domain d2c0pb2: 2c0p B:4-543

Lineage for d2c0pb2 (2c0p B:4-543)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (6 proteins)
   automatically mapped to Pfam PF00135

6. Protein automated matches [190065] (6 species)
   not a true protein

7. Species Mouse (Mus musculus) [TaxId:10090] [187006] (55 PDB entries)

8. Domain d2c0pb2: 2c0p B:4-543 [129601]
   Other proteins in same PDB: d2c0pb3
   automated match to d1maac_
   complexed with atj

Details for d2c0pb2

PDB Entry: 2c0p, 2.5 Å

PDB Description: aged form of mouse acetylcholinesterase inhibited by tabun

PDB Compounds: (B:) acetylcholinesterase

SCOPe Domain Sequences for d2c0pb2:

Sequence, based on SEQRES records:

>d2c0pb2 c.69.1.1 (B:4-543) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
edpqllvrvrggqlrgirlkapggpvsaflgipfaeppvgsrrfmppepkrpwsgvldat
tfqnvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprpasptpvliwiygggf
ysgaasldvydgrflaqvegavlvsmnyrvgtfgflalpgsreapgnvglldqrlalqwv
qeniaafggdpmsvtlfgesagaasvgmhilslpsrslfhravlqsgtpngpwatvsage
arrratllarlvgcppggaggndteliaclrtrpaqdlvdhewhvlpqesifrfsfvpvv
dgdflsdtpealintgdfqdlqvlvgvvkdegsyflvygvpgfskdneslisraqflagv
rigvpqasdlaaeavvlhytdwlhpedpthlrdamsavvgdhnvvcpvaqlagrlaaqga
rvyayifehrastltwplwmgvphgyeiefifglpldpslnytteerifaqrlmkywtnf
artgdpndprdskspqwppyttaaqqyvslnlkplevrrglraqtcafwnrflpkllsat

Sequence, based on observed residues (ATOM records):

>d2c0pb2 c.69.1.1 (B:4-543) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
edpqllvrvrggqlrgirlkapggpvsaflgipfaeppvgsrrfmppepkrpwsgvldat
tfqnvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprpasptpvliwiygggf
ysgaasldvydgrflaqvegavlvsmnyrvgtfgflalpgsreapgnvglldqrlalqwv
qeniaafggdpmsvtlfgesagaasvgmhilslpsrslfhravlqsgtpngpwatvsage
arrratllarlvgcndteliaclrtrpaqdlvdhewhvlpqesifrfsfvpvvdgdflsd
tpealintgdfqdlqvlvgvvkdegsyflvygvpgfskdneslisraqflagvrigvpqa
sdlaaeavvlhytdwlhpedpthlrdamsavvgdhnvvcpvaqlagrlaaqgarvyayif
ehrastltwplwmgvphgyeiefifglpldpslnytteerifaqrlmkywtnfartgdpn
dprdskspqwppyttaaqqyvslnlkplevrrglraqtcafwnrflpkllsat

Timeline for d2c0pb2:

• d2c0pb2 first appeared in SCOP 1.73, called d2c0pb1
  
• d2c0pb2 was called d2c0pb_ in SCOPe 2.05
  
• d2c0pb2 appears in SCOPe 2.07
  
• d2c0pb2 appears in the current release, SCOPe 2.08