Lineage for d2bxva_ (2bxv A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2080000Superfamily c.1.4: FMN-linked oxidoreductases [51395] (2 families) (S)
  5. 2080001Family c.1.4.1: FMN-linked oxidoreductases [51396] (19 protein domains)
  6. 2080389Protein automated matches [190228] (18 species)
    not a true protein
  7. 2080395Species Human (Homo sapiens) [TaxId:9606] [187000] (8 PDB entries)
  8. 2080403Domain d2bxva_: 2bxv A: [129445]
    automated match to d1d3ga_
    complexed with 3ft, act, fmn, oro, so4

Details for d2bxva_

PDB Entry: 2bxv (more details), 2.15 Å

PDB Description: dual binding mode of a novel series of dhodh inhibitors
PDB Compounds: (A:) dihydroorotate dehydrogenase

SCOPe Domain Sequences for d2bxva_:

Sequence, based on SEQRES records: (download)

>d2bxva_ c.1.4.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
matgderfyaehlmptlqglldpesahrlavrftslgllprarfqdsdmlevrvlghkfr
npvgiaagfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygf
nshglsvvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladyl
vvnvsspntaglrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkedia
svvkelgidglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvp
iigvggvssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtda
igadhrr

Sequence, based on observed residues (ATOM records): (download)

>d2bxva_ c.1.4.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
matgderfyaehlmptlqglldpesahrlavrftslgllpfqdsdmlevrvlghkfrnpv
giaagfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfnsh
glsvvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvvn
vsspntaglgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasvvkelg
idglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpiigvggv
ssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdaigadhrr

SCOPe Domain Coordinates for d2bxva_:

Click to download the PDB-style file with coordinates for d2bxva_.
(The format of our PDB-style files is described here.)

Timeline for d2bxva_: