Lineage for d2brna_ (2brn A:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2220941Protein automated matches [190091] (17 species)
    not a true protein
  7. 2221040Species Human (Homo sapiens) [TaxId:9606] [188447] (653 PDB entries)
  8. 2221736Domain d2brna_: 2brn A: [129003]
    automated match to d3nlba_
    complexed with df1

Details for d2brna_

PDB Entry: 2brn (more details), 2.8 Å

PDB Description: structure-based design of novel chk1 inhibitors: insights into hydrogen bonding and protein-ligand affinity
PDB Compounds: (A:) Serine/threonine-protein kinase Chk1

SCOPe Domain Sequences for d2brna_:

Sequence, based on SEQRES records: (download)

>d2brna_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicinkmlnhe
nvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgig
ithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefh
aepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhki
lvenpsaritipdikkdrwynkplkkgakrp

Sequence, based on observed residues (ATOM records): (download)

>d2brna_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vedwdlvqtlgegaygevqlavnrvteeavavkivdmkrcpenikkeicinkmlnhenvv
kfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigith
rdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaep
vdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilve
npsaritipdikkdrwynkplkkgakrp

SCOPe Domain Coordinates for d2brna_:

Click to download the PDB-style file with coordinates for d2brna_.
(The format of our PDB-style files is described here.)

Timeline for d2brna_: