SCOPe 2.05: Domain d2brfa1: 2brf A:8-108

Lineage for d2brfa1 (2brf A:8-108)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.26: SMAD/FHA domain [49878] (1 superfamily)
   sandwich; 11 strands in 2 sheets; greek-key

4. Superfamily b.26.1: SMAD/FHA domain [49879] (5 families)
   has a few short helices inserted in loops

5. Family b.26.1.2: FHA domain [49885] (12 proteins)

6. Protein Polynucleotide kinase 3'-phosphatase [101628] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [141134] (1 PDB entry)
   Uniprot Q96T60 8-108

8. Domain d2brfa1: 2brf A:8-108 [128996]
   complexed with so4

Details for d2brfa1

PDB Entry: 2brf, 1.4 Å

PDB Description: crystal structure of the fha domain of human polynucleotide kinase 3' phosphatase

PDB Compounds: (A:) bifunctional polynucleotide phosphatase/kinase

SCOPe Domain Sequences for d2brfa1:

Sequence, based on SEQRES records:

>d2brfa1 b.26.1.2 (A:8-108) Polynucleotide kinase 3'-phosphatase {Human (Homo sapiens) [TaxId: 9606]}
grlwlesppgeappiflpsdgqalvlgrgpltqvtdrkcsrtqvelvadpetrtvavkql
gvnpsttgtqelkpglegslgvgdtlylvnglhpltlrwee

Sequence, based on observed residues (ATOM records):

>d2brfa1 b.26.1.2 (A:8-108) Polynucleotide kinase 3'-phosphatase {Human (Homo sapiens) [TaxId: 9606]}
grlwlesppgeappiflpsdgqalvlgrgpltqvtdrkcsrtqvelvadpetrtvavkql
gvnpsttgqelkpglegslgvgdtlylvnglhpltlrwee

Timeline for d2brfa1:

• d2brfa1 first appeared in SCOP 1.73
  
• d2brfa1 appears in SCOPe 2.04
  
• d2brfa1 appears in SCOPe 2.06
  
• d2brfa1 appears in the current release, SCOPe 2.08