SCOPe 2.07: Domain d2br5e_: 2br5 E:

Lineage for d2br5e_ (2br5 E:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families)

5. Family c.66.1.50: CmcI-like [142632] (1 protein)
   Pfam PF04989; may have evolved different enzymatic activity

6. Protein Cephalosporin hydroxylase CmcI [142633] (1 species)

7. Species Streptomyces clavuligerus [TaxId:1901] [142634] (5 PDB entries)
   Uniprot O85726 2-233

8. Domain d2br5e_: 2br5 E: [128991]
   automated match to d2bm8a1
   complexed with sah

Details for d2br5e_

PDB Entry: 2br5, 2.83 Å

PDB Description: cmci-n160 sah

PDB Compounds: (E:) cephalosporin hydroxylase cmci

SCOPe Domain Sequences for d2br5e_:

Sequence; same for both SEQRES and ATOM records:

>d2br5e_ c.66.1.50 (E:) Cephalosporin hydroxylase CmcI {Streptomyces clavuligerus [TaxId: 1901]}
dysrqnfqdlnlfrglgedpayhppvltdrprdwpldrwaeaprdlgysdfspyqwrglr
mlkdpdtqavyhdmlwelrprtivelgvynggslawfrdltkimgidcqvigidrdlsrc
qipasdmenitlhqgdcsdlttfehlremahplifidnahantfnimkwavdhlleegdy
fiiedmipywyryapqlfseylgafrdvlsmdmlyanassqldrgvlrrv

Timeline for d2br5e_:

• d2br5e_ first appeared in SCOP 1.73, called d2br5e1
  
• d2br5e_ appears in SCOPe 2.06
  
• d2br5e_ appears in the current release, SCOPe 2.08