SCOP 1.75: Domain d2br5a1: 2br5 A:8-233

Lineage for d2br5a1 (2br5 A:8-233)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (57 families)

5. Family c.66.1.50: CmcI-like [142632] (1 protein)
   Pfam PF04989; may have evolved different enzymatic activity

6. Protein Cephalosporin hydroxylase CmcI [142633] (1 species)

7. Species Streptomyces clavuligerus [TaxId:1901] [142634] (5 PDB entries)
   Uniprot O85726 2-233

8. Domain d2br5a1: 2br5 A:8-233 [128988]
   automatically matched to 2BM8 A:2-233
   complexed with sah; mutant

Details for d2br5a1

PDB Entry: 2br5, 2.83 Å

PDB Description: cmci-n160 sah

PDB Compounds: (A:) cephalosporin hydroxylase cmci

SCOP Domain Sequences for d2br5a1:

Sequence; same for both SEQRES and ATOM records:

>d2br5a1 c.66.1.50 (A:8-233) Cephalosporin hydroxylase CmcI {Streptomyces clavuligerus [TaxId: 1901]}
nfqdlnlfrglgedpayhppvltdrprdwpldrwaeaprdlgysdfspyqwrglrmlkdp
dtqavyhdmlwelrprtivelgvynggslawfrdltkimgidcqvigidrdlsrcqipas
dmenitlhqgdcsdlttfehlremahplifidnahantfnimkwavdhlleegdyfiied
mipywyryapqlfseylgafrdvlsmdmlyanassqldrgvlrrva

Timeline for d2br5a1:

• d2br5a1 first appeared in SCOP 1.73
  
• d2br5a1 is called d2br5a_ in SCOPe 2.01
  
• d2br5a1 appears in the current release, SCOPe 2.08, called d2br5a_