SCOP 1.73: Domain d2br4b1: 2br4 B:3-233

Lineage for d2br4b1 (2br4 B:3-233)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (52 families)

5. Family c.66.1.50: CmcI-like [142632] (1 protein)
   Pfam PF04989; may have evolved different enzymatic activity

6. Protein Cephalosporin hydroxylase CmcI [142633] (1 species)

7. Species Streptomyces clavuligerus [TaxId:1901] [142634] (5 PDB entries)

8. Domain d2br4b1: 2br4 B:3-233 [128983]
   automatically matched to 2BR3 A:2-233
   complexed with mg, p4c, peg, sam; mutant

Details for d2br4b1

PDB Entry: 2br4, 2.59 Å

PDB Description: cmci-d160 mg-sam

PDB Compounds: (B:) cephalosporin hydroxylase cmci

SCOP Domain Sequences for d2br4b1:

Sequence; same for both SEQRES and ATOM records:

>d2br4b1 c.66.1.50 (B:3-233) Cephalosporin hydroxylase CmcI {Streptomyces clavuligerus [TaxId: 1901]}
dysrqnfldlnlfrglgedpayhppvltdrprdwpldrwaeaprdlgysdfspyqwrglr
mlkdpdtqavyhdmlwelrprtivelgvynggslawfrdltkimgidcqvigidrdlsrc
qipasdmenitlhqgdcsdlttfehlremahplifiddahantfnimkwavdhlleegdy
fiiedmipywyryapqlfseylgafrdvlsmdmlyanassqldrgvlrrva

Timeline for d2br4b1:

• d2br4b1 is new in SCOP 1.73
  
• d2br4b1 appears in SCOP 1.75
  
• d2br4b1 appears in the current release, SCOPe 2.08, called d2br4b_