SCOPe 2.05: Domain d2bm2a_: 2bm2 A:

Lineage for d2bm2a_ (2bm2 A:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein beta-Tryptase [50546] (1 species)
   ring-like tetramer with active sites facing a central pore

7. Species Human (Homo sapiens) [TaxId:9606] [50547] (18 PDB entries)

8. Domain d2bm2a_: 2bm2 A: [128758]
   automated match to d1a0la_
   complexed with pm2

Details for d2bm2a_

PDB Entry: 2bm2, 2.2 Å

PDB Description: human beta-ii tryptase in complex with 4-(3-aminomethyl-phenyl)- piperidin-1-yl-(5-phenethyl- pyridin-3-yl)-methanone

PDB Compounds: (A:) human beta2 tryptase

SCOPe Domain Sequences for d2bm2a_:

Sequence; same for both SEQRES and ATOM records:

>d2bm2a_ b.47.1.2 (A:) beta-Tryptase {Human (Homo sapiens) [TaxId: 9606]}
ivggqeaprskwpwqvslrvhgpywmhfcggslihpqwvltaahcvgpdvkdlaalrvql
reqhlyyqdqllpvsriivhpqfytaqigadialleleepvkvsshvhtvtlppasetfp
pgmpcwvtgwgdvdnderlpppfplkqvkvpimenhicdakyhlgaytgddvrivrddml
cagntrrdscqgdsggplvckvngtwlqagvvswgegcaqpnrpgiytrvtyyldwihhy
vpk

Timeline for d2bm2a_:

• d2bm2a_ first appeared in SCOP 1.73, called d2bm2a1
  
• d2bm2a_ appears in SCOPe 2.04
  
• d2bm2a_ appears in SCOPe 2.06
  
• d2bm2a_ appears in the current release, SCOPe 2.08