SCOPe 2.08: Domain d2bkaa1: 2bka A:5-236

Lineage for d2bkaa1 (2bka A:5-236)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
   has additional subdomain(s) that are not in the common domain
   

6. Protein TAT-interacting protein TIP30 [141904] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [141905] (1 PDB entry)
   Uniprot Q9BUP3 5-236

8. Domain d2bkaa1: 2bka A:5-236 [128666]
   complexed with gol, ndp, pe8, so4

Details for d2bkaa1

PDB Entry: 2bka, 1.7 Å

PDB Description: cc3(tip30)crystal strutcure

PDB Compounds: (A:) tat-interacting protein tip30

SCOPe Domain Sequences for d2bkaa1:

Sequence; same for both SEQRES and ATOM records:

>d2bkaa1 c.2.1.2 (A:5-236) TAT-interacting protein TIP30 {Human (Homo sapiens) [TaxId: 9606]}
ealsklredfrmqnksvfilgasgetgrvllkeileqglfskvtligrrkltfdeeaykn
vnqevvdfeklddyasafqghdvgfcclgttrgkagaegfvrvdrdyvlksaelakaggc
khfnllsskgadkssnflylqvkgeveakveelkfdrysvfrpgvllcdrqesrpgewlv
rkffgslpdswasghsvpvvtvvramlnnvvrprdkqmellenkaihdlgka

Timeline for d2bkaa1:

• d2bkaa1 first appeared in SCOP 1.73
  
• d2bkaa1 appears in SCOPe 2.07