SCOPe 2.08: Domain d2bhrb2: 2bhr B:171-482

Lineage for d2bhrb2 (2bhr B:171-482)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.14: RNA helicase [52724] (7 proteins)
   duplication: consists of two similar domains, one binds NTP and the other binds RNA; also contains an all-alpha subdomain in the C-terminal extension

6. Protein Dengue virus helicase, N-terminal domain [418960] (1 species)

7. Species Dengue virus type 2 [TaxId:11060] [419422] (2 PDB entries)
   Uniprot Q91H74

8. Domain d2bhrb2: 2bhr B:171-482 [128545]
   Other proteins in same PDB: d2bhra1, d2bhrb1, d2bhrb3
   automated match to d2bhra2
   complexed with so4
   has additional subdomain(s) that are not in the common domain

Details for d2bhrb2

PDB Entry: 2bhr, 2.8 Å

PDB Description: dengue virus rna helicase

PDB Compounds: (B:) RNA helicase

SCOPe Domain Sequences for d2bhrb2:

Sequence, based on SEQRES records:

>d2bhrb2 c.37.1.14 (B:171-482) Dengue virus helicase, N-terminal domain {Dengue virus type 2 [TaxId: 11060]}
siednpeieddifrkkrltimdlhpgagktkrylpaivreaikrglrtlilaptrvvaae
meealrglpiryqtpairaehtgreivdlmchatftmrllspirvpnynliimdeahftd
pasiaargyistrvemgeaagifmtatppgsrdpfpqsnapimdeereiperswnsghew
vtdfkgktvwfvpsikagndiaaclrkngkkviqlsrktfdseyiktrtndwdfvvttdi
semganfkaervidprrcmkpviltdgeervilagpmpvthssaaqrrgrvgrnpknend
qyiymgeplend

Sequence, based on observed residues (ATOM records):

>d2bhrb2 c.37.1.14 (B:171-482) Dengue virus helicase, N-terminal domain {Dengue virus type 2 [TaxId: 11060]}
siednpeieddifrkkrltimdlhpgagktkrylpaivreaikrglrtlilaptrvvaae
meealrglpiryqreivdlmchatftmrllspirvpnynliimdeahftdpasiaargyi
strvemgeaagifmtatppgsrdpfpqsnapimdeereiperswnsghewvtdfkgktvw
fvpsikagndiaaclrkngkkviqlsrktfdseyiktrtndwdfvvttdisemganfkae
rvidprrcmkpviltdgeervilagpmpvthssaaqrrgrvgrnpknendqyiymgeple
nd

Timeline for d2bhrb2:

• d2bhrb2 first appeared in SCOP 1.73
  
• d2bhrb2 appears in SCOPe 2.07