SCOPe 2.06: Domain d2beda_: 2bed A:

Lineage for d2beda_ (2bed A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (25 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.6: Protein prenylyltransferase [48439] (2 families)

5. Family a.118.6.1: Protein prenylyltransferase [48440] (3 proteins)

6. Protein Protein farnesyltransferase alpha-subunit [48441] (2 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [48442] (51 PDB entries)
   Uniprot Q04631 55-369

8. Domain d2beda_: 2bed A: [128375]
   Other proteins in same PDB: d2bedb_
   automated match to d1o1ra_
   complexed with 736, fpp, zn

Details for d2beda_

PDB Entry: 2bed, 2.7 Å

PDB Description: structure of fpt bound to inhibitor sch207736

PDB Compounds: (A:) Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit

SCOPe Domain Sequences for d2beda_:

Sequence; same for both SEQRES and ATOM records:

>d2beda_ a.118.6.1 (A:) Protein farnesyltransferase alpha-subunit {Norway rat (Rattus norvegicus) [TaxId: 10116]}
gflsldsptyvlyrdraewadidpvpqndgpspvvqiiysekfrdvydyfravlqrders
erafkltrdaielnaanytvwhfrrvllrslqkdlqeemnyitaiieeqpknyqvwhhrr
vlvewlkdpsqelefiadilnqdaknyhawqhrqwviqefrlwdnelqyvdqllkedvrn
nsvwnqrhfvisnttgysdravlerevqytlemiklvphnesawnylkgilqdrglsryp
nllnqlldlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirk
eywryigrslqsk

Timeline for d2beda_:

• d2beda_ first appeared in SCOP 1.73, called d2beda1
  
• d2beda_ appears in SCOPe 2.05
  
• d2beda_ appears in SCOPe 2.07
  
• d2beda_ appears in the current release, SCOPe 2.08