SCOPe 2.02: Domain d2bdja1: 2bdj A:257-521

Lineage for d2bdja1 (2bdj A:257-521)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein c-src tyrosine kinase [56155] (2 species)
   PTK group; Src subfamily; non-membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56156] (8 PDB entries)

8. Domain d2bdja1: 2bdj A:257-521 [128338]
   automatically matched to d1fmk_3
   complexed with het

Details for d2bdja1

PDB Entry: 2bdj, 2.5 Å

PDB Description: Src kinase in complex with inhibitor AP23464

PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase Src

SCOPe Domain Sequences for d2bdja1:

Sequence, based on SEQRES records:

>d2bdja1 d.144.1.7 (A:257-521) c-src tyrosine kinase {Human (Homo sapiens) [TaxId: 9606]}
kdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvmkk
lrheklvqlyavvseepiyivteymskgslldflkgetgkylrlpqlvdmaaqiasgmay
vermnyvhrdlraanilvgenlvckvadfglarliedneytarqgakfpikwtapeaaly
grftiksdvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmc
qcwrkepeerptfeylqafledyft

Sequence, based on observed residues (ATOM records):

>d2bdja1 d.144.1.7 (A:257-521) c-src tyrosine kinase {Human (Homo sapiens) [TaxId: 9606]}
kdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvmkk
lrheklvqlyavvseepiyivteymskgslldflkgetgkylrlpqlvdmaaqiasgmay
vermnyvhrdlraanilvgenlvckvadfglarliefpikwtapeaalygrftiksdvws
fgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmcqcwrkepeerp
tfeylqafledyft

Timeline for d2bdja1:

• d2bdja1 first appeared in SCOP 1.73
  
• d2bdja1 appears in SCOPe 2.01
  
• d2bdja1 is called d2bdja_ in SCOPe 2.03
  
• d2bdja1 appears in the current release, SCOPe 2.08, called d2bdja_