SCOP 1.73: Domain d2b8ua1: 2b8u A:1-129

Lineage for d2b8ua1 (2b8u A:1-129)

1. Root: SCOP 1.73

2. Class a: All alpha proteins [46456] (258 folds)

3. Fold a.26: 4-helical cytokines [47265] (1 superfamily)
   core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections

4. Superfamily a.26.1: 4-helical cytokines [47266] (3 families)
   there are two different topoisomers of this fold with different entanglements of the two crossover connections

5. Family a.26.1.2: Short-chain cytokines [47286] (11 proteins)

6. Protein Interleukin-4 (IL-4) [47291] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [47292] (14 PDB entries)

8. Domain d2b8ua1: 2b8u A:1-129 [128117]
   automatically matched to d1itl__
   complexed with so4

Details for d2b8ua1

PDB Entry: 2b8u, 1.8 Å

PDB Description: Crystal structure of wildtype human Interleukin-4

PDB Compounds: (A:) interleukin-4

SCOP Domain Sequences for d2b8ua1:

Sequence; same for both SEQRES and ATOM records:

>d2b8ua1 a.26.1.2 (A:1-129) Interleukin-4 (IL-4) {Human (Homo sapiens) [TaxId: 9606]}
hkcditlqeiiktlnslteqktlcteltvtdifaaskntteketfcraatvlrqfyshhe
kdtrclgataqqfhrhkqlirflkrldrnlwglaglnscpvkeanqstlenflerlktim
rekyskcss

Timeline for d2b8ua1:

• d2b8ua1 is new in SCOP 1.73
  
• d2b8ua1 appears in SCOP 1.75
  
• d2b8ua1 appears in the current release, SCOPe 2.08, called d2b8ua_