Lineage for d2b8ua1 (2b8u A:1-129)

  1. Root: SCOP 1.73
  2. 631650Class a: All alpha proteins [46456] (258 folds)
  3. 639436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 639437Superfamily a.26.1: 4-helical cytokines [47266] (3 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 639507Family a.26.1.2: Short-chain cytokines [47286] (11 proteins)
  6. 639558Protein Interleukin-4 (IL-4) [47291] (1 species)
  7. 639559Species Human (Homo sapiens) [TaxId:9606] [47292] (14 PDB entries)
  8. 639560Domain d2b8ua1: 2b8u A:1-129 [128117]
    automatically matched to d1itl__
    complexed with so4

Details for d2b8ua1

PDB Entry: 2b8u (more details), 1.8 Å

PDB Description: Crystal structure of wildtype human Interleukin-4
PDB Compounds: (A:) interleukin-4

SCOP Domain Sequences for d2b8ua1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2b8ua1 a.26.1.2 (A:1-129) Interleukin-4 (IL-4) {Human (Homo sapiens) [TaxId: 9606]}
hkcditlqeiiktlnslteqktlcteltvtdifaaskntteketfcraatvlrqfyshhe
kdtrclgataqqfhrhkqlirflkrldrnlwglaglnscpvkeanqstlenflerlktim
rekyskcss

SCOP Domain Coordinates for d2b8ua1:

Click to download the PDB-style file with coordinates for d2b8ua1.
(The format of our PDB-style files is described here.)

Timeline for d2b8ua1: