SCOPe 2.06: Domain d2b8oh_: 2b8o H:

Lineage for d2b8oh_ (2b8o H:)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein Coagulation factor VIIa [50550] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50551] (88 PDB entries)
   Uniprot P08709 213-466 ! Uniprot P08709 213-446

8. Domain d2b8oh_: 2b8o H: [128095]
   Other proteins in same PDB: d2b8ol1, d2b8ol2, d2b8ol3, d2b8ot1, d2b8ot2
   automated match to d1cvwh_
   complexed with 0gj, ca, cl, fuc, glc, mg, na, zn

Details for d2b8oh_

PDB Entry: 2b8o, 2.8 Å

PDB Description: crystal structure of glu-gly-arg-chloromethyl ketone-factor viia/soluble tissue factor complex

PDB Compounds: (H:) Coagulation factor VII heavy chain

SCOPe Domain Sequences for d2b8oh_:

Sequence; same for both SEQRES and ATOM records:

>d2b8oh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

Timeline for d2b8oh_:

• d2b8oh_ first appeared in SCOP 1.73, called d2b8oh1
  
• d2b8oh_ appears in SCOPe 2.05
  
• d2b8oh_ appears in SCOPe 2.07
  
• d2b8oh_ appears in the current release, SCOPe 2.08