SCOPe 2.04: Domain d2b7oa1: 2b7o A:1-462

Lineage for d2b7oa1 (2b7o A:1-462)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (9 families)
   Common fold covers whole protein structure

5. Family c.1.10.8: Class-II DAHP synthetase [141840] (2 proteins)
   Pfam PF01474

6. Protein Probable DAHP synthetase AroG, phenylalanine-repressible [141841] (1 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [141842] (5 PDB entries)
   Uniprot O53512 1-462

8. Domain d2b7oa1: 2b7o A:1-462 [128047]
   complexed with ce1, mn, pep, so4

Details for d2b7oa1

PDB Entry: 2b7o, 2.3 Å

PDB Description: The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase from Mycobacterium tuberculosis

PDB Compounds: (A:) 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase arog

SCOPe Domain Sequences for d2b7oa1:

Sequence, based on SEQRES records:

>d2b7oa1 c.1.10.8 (A:1-462) Probable DAHP synthetase AroG, phenylalanine-repressible {Mycobacterium tuberculosis [TaxId: 1773]}
mnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtv
pseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmp
vvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaam
nlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqt
aeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqvia
npvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghq
viwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvtec
lggaqdisetdlagryetacdprlntqqslelaflvaemlrd

Sequence, based on observed residues (ATOM records):

>d2b7oa1 c.1.10.8 (A:1-462) Probable DAHP synthetase AroG, phenylalanine-repressible {Mycobacterium tuberculosis [TaxId: 1773]}
mnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtv
pseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmp
vvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaam
nlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqt
aeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqvia
npvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghq
viwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvtla
gryetacdprlntqqslelaflvaemlrd

Timeline for d2b7oa1:

• d2b7oa1 first appeared in SCOP 1.73
  
• d2b7oa1 appears in SCOPe 2.03
  
• d2b7oa1 appears in SCOPe 2.05
  
• d2b7oa1 appears in the current release, SCOPe 2.08