Lineage for d2b7dt1 (2b7d T:6-108)

  1. Root: SCOPe 2.01
  2. 929298Class b: All beta proteins [48724] (174 folds)
  3. 929299Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 935729Superfamily b.1.2: Fibronectin type III [49265] (2 families) (S)
  5. 935730Family b.1.2.1: Fibronectin type III [49266] (45 proteins)
    Pfam PF00041
  6. 935829Protein Extracellular region of human tissue factor [49267] (2 species)
    tandem of fibronectin type III domains
  7. 935858Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [49269] (18 PDB entries)
  8. 935883Domain d2b7dt1: 2b7d T:6-108 [128034]
    Other proteins in same PDB: d2b7dh_
    automatically matched to d1a21a1
    complexed with c1b

Details for d2b7dt1

PDB Entry: 2b7d (more details), 2.24 Å

PDB Description: factor viia inhibitors: chemical optimization, preclinical pharmacokinetics, pharmacodynamics, and efficacy in a baboon thrombosis model
PDB Compounds: (T:) tissue factor

SCOPe Domain Sequences for d2b7dt1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2b7dt1 b.1.2.1 (T:6-108) Extracellular region of human tissue factor {Rabbit (Oryctolagus cuniculus) [TaxId: 9986]}
tvaaynltwkstnfktilewepkpvnqvytvqistksgdwkskcfyttdtecdltdeivk
dvkqtylarvfsypagnvestgsageplyenspeftpyletnl

SCOPe Domain Coordinates for d2b7dt1:

Click to download the PDB-style file with coordinates for d2b7dt1.
(The format of our PDB-style files is described here.)

Timeline for d2b7dt1:

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Domains from same chain:
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d2b7dt2
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Domains from other chains:
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d2b7dh_