SCOPe 2.01: Domain d2b6ab_: 2b6a B:

Lineage for d2b6ab_ (2b6a B:)

1. Root: SCOPe 2.01

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)

6. Protein HIV-1 reverse transcriptase [56689] (3 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (126 PDB entries)
   Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582 ! Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584 ! Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595

8. Domain d2b6ab_: 2b6a B: [127975]
   automated match to d1bqmb_
   complexed with t50

Details for d2b6ab_

PDB Entry: 2b6a, 2.65 Å

PDB Description: crystal structure of hiv-1 reverse transcriptase (rt) in complex with thr-50

PDB Compounds: (B:) Reverse transcriptase P51 SUBUNIT

SCOPe Domain Sequences for d2b6ab_:

Sequence; same for both SEQRES and ATOM records:

>d2b6ab_ e.8.1.2 (B:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwy

Timeline for d2b6ab_:

• d2b6ab_ first appeared in SCOP 1.73, called d2b6ab1
  
• d2b6ab_ was called d2b6ab1 in SCOP 1.75
  
• d2b6ab_ appears in SCOPe 2.02
  
• d2b6ab_ appears in the current release, SCOPe 2.08