Lineage for d2b5ia1 (2b5i A:6-133)

  1. Root: SCOP 1.73
  2. 631650Class a: All alpha proteins [46456] (258 folds)
  3. 639436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 639437Superfamily a.26.1: 4-helical cytokines [47266] (3 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 639507Family a.26.1.2: Short-chain cytokines [47286] (11 proteins)
  6. 639530Protein Interleukin-2 (IL-2) [47301] (1 species)
  7. 639531Species Human (Homo sapiens) [TaxId:9606] [47302] (14 PDB entries)
  8. 639539Domain d2b5ia1: 2b5i A:6-133 [127895]
    Other proteins in same PDB: d2b5ib1, d2b5ib2, d2b5ic1, d2b5ic2, d2b5id1, d2b5id2
    automatically matched to d1m48b_
    complexed with nag; mutant

Details for d2b5ia1

PDB Entry: 2b5i (more details), 2.3 Å

PDB Description: cytokine receptor complex
PDB Compounds: (A:) interleukin-2

SCOP Domain Sequences for d2b5ia1:

Sequence, based on SEQRES records: (download)

>d2b5ia1 a.26.1.2 (A:6-133) Interleukin-2 (IL-2) {Human (Homo sapiens) [TaxId: 9606]}
stkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeelkp
leevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnrwitfc
qsiistlt

Sequence, based on observed residues (ATOM records): (download)

>d2b5ia1 a.26.1.2 (A:6-133) Interleukin-2 (IL-2) {Human (Homo sapiens) [TaxId: 9606]}
stkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeelkp
leevlnlaqslrprdlisninvivlelkgfmceyadetativeflnrwitfcqsiistlt

SCOP Domain Coordinates for d2b5ia1:

Click to download the PDB-style file with coordinates for d2b5ia1.
(The format of our PDB-style files is described here.)

Timeline for d2b5ia1: