SCOPe 2.08: Domain d2b50b_: 2b50 B:

Lineage for d2b50b_ (2b50 B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator-activated receptor delta, PPAR-DELTA [48526] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48527] (37 PDB entries)

8. Domain d2b50b_: 2b50 B: [127873]
   automated match to d1gwxa_
   complexed with b7g, ca, vca

Details for d2b50b_

PDB Entry: 2b50, 2 Å

PDB Description: human nuclear receptor-ligand complex 2

PDB Compounds: (B:) Peroxisome proliferator activated receptor delta

SCOPe Domain Sequences for d2b50b_:

Sequence, based on SEQRES records:

>d2b50b_ a.123.1.1 (B:) Peroxisome proliferator-activated receptor delta, PPAR-DELTA {Human (Homo sapiens) [TaxId: 9606]}
npqvadlkafskhiynaylknfnmtkkkarsiltgkashtapfvihdietlwqaekglvw
kqlvnglppykeisvhvfyrcqcttvetvreltefaksipsfsslflndqvtllkygvhe
aifamlasivnkdgllvangsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdl
alfiaaiilcgdrpglmnvprveaiqdtilralefhlqanhpdaqqlfpkllqkmadlrq
lvtehaqmmqrikktetetslhpllqeiykd

Sequence, based on observed residues (ATOM records):

>d2b50b_ a.123.1.1 (B:) Peroxisome proliferator-activated receptor delta, PPAR-DELTA {Human (Homo sapiens) [TaxId: 9606]}
npqvadlkafskhiynaylknfnmtkkkarsiltghtapfvihdietlwqaekglvwklp
pykeisvhvfyrcqcttvetvreltefaksipsfsslflndqvtllkygvheaifamlas
ivnkdgllvangsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdlalfiaaii
lcgdrpglmnvprveaiqdtilralefhlqanhpdaqqlfpkllqkmadlrqlvtehaqm
mqrikktetetslhpllqeiykd

Timeline for d2b50b_:

• d2b50b_ first appeared in SCOP 1.73, called d2b50b1
  
• d2b50b_ appears in SCOPe 2.07