Lineage for d2b4sa1 (2b4s A:2-292)

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 698670Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 698671Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (5 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 698721Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (6 proteins)
    has an extension to the beta-sheet of 3 antiparallel strands before strand 4
  6. 698752Protein Tyrosine phosphatase [52806] (7 species)
  7. 698753Species Human (Homo sapiens), 1B [TaxId:9606] [52807] (91 PDB entries)
  8. 698808Domain d2b4sa1: 2b4s A:2-292 [127853]
    Other proteins in same PDB: d2b4sb1, d2b4sd1
    automatically matched to d1g1ga_
    complexed with so4

Details for d2b4sa1

PDB Entry: 2b4s (more details), 2.3 Å

PDB Description: crystal structure of a complex between ptp1b and the insulin receptor tyrosine kinase
PDB Compounds: (A:) Tyrosine-protein phosphatase, non-receptor type 1

SCOP Domain Sequences for d2b4sa1:

Sequence, based on SEQRES records: (download)

>d2b4sa1 c.45.1.2 (A:2-292) Tyrosine phosphatase {Human (Homo sapiens), 1B [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d2b4sa1 c.45.1.2 (A:2-292) Tyrosine phosphatase {Human (Homo sapiens), 1B [TaxId: 9606]}

SCOP Domain Coordinates for d2b4sa1:

Click to download the PDB-style file with coordinates for d2b4sa1.
(The format of our PDB-style files is described here.)

Timeline for d2b4sa1: