SCOPe 2.05: Domain d2b4rr2: 2b4r R:153-318

Lineage for d2b4rr2 (2b4r R:153-318)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.81: FwdE/GAPDH domain-like [55346] (4 superfamilies)
   core: alpha-beta-alpha-beta(3); mixed sheet: 2134, strand 2 is parallel to strand 1

4. Superfamily d.81.1: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain [55347] (5 families)
   N-terminal domain is the classic Rossmann-fold

5. Family d.81.1.1: GAPDH-like [55348] (6 proteins)
   has many additional secondary structures

6. Protein Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) [55349] (19 species)

7. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [143536] (3 PDB entries)
   Uniprot Q8IKK7 153-318! Uniprot Q8T6B1 153-318

8. Domain d2b4rr2: 2b4r R:153-318 [127852]
   Other proteins in same PDB: d2b4ro1, d2b4rp1, d2b4rq1, d2b4rr1
   automated match to d2b4ro2
   complexed with aes, gol, nad

Details for d2b4rr2

PDB Entry: 2b4r, 2.25 Å

PDB Description: crystal structure of glyceraldehyde-3-phosphate dehydrogenase from plasmodium falciparum at 2.25 angstrom resolution reveals intriguing extra electron density in the active site

PDB Compounds: (R:) glyceraldehyde-3-phosphate dehydrogenase

SCOPe Domain Sequences for d2b4rr2:

Sequence; same for both SEQRES and ATOM records:

>d2b4rr2 d.81.1.1 (R:153-318) Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
cttnclaplakvindrfgiveglmttvhastanqlvvdgpskggkdwragrcalsniipa
stgaakavgkvlpelngkltgvafrvpigtvsvvdlvcrlqkpakyeevaleikkaaegp
lkgilgytedevvsqdfvhdnrssifdmkaglalndnffklvswyd

Timeline for d2b4rr2:

• d2b4rr2 first appeared in SCOP 1.73
  
• d2b4rr2 appears in SCOPe 2.04
  
• d2b4rr2 appears in SCOPe 2.06
  
• d2b4rr2 appears in the current release, SCOPe 2.08