SCOPe 2.08: Domain d2b4ja_: 2b4j A:

Lineage for d2b4ja_ (2b4j A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (18 families)
   consists of one domain of this fold

5. Family c.55.3.2: Retroviral integrase, catalytic domain [53107] (2 proteins)
   Pfam PF00665

6. Protein Retroviral integrase, catalytic domain [53108] (5 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [53110] (74 PDB entries)

8. Domain d2b4ja_: 2b4j A: [127833]
   Other proteins in same PDB: d2b4jc1, d2b4jc2, d2b4jd2, d2b4jd3
   automated match to d1bi4c_
   complexed with gol, po4

Details for d2b4ja_

PDB Entry: 2b4j, 2.02 Å

PDB Description: structural basis for the recognition between hiv-1 integrase and ledgf/p75

PDB Compounds: (A:) Integrase (IN)

SCOPe Domain Sequences for d2b4ja_:

Sequence, based on SEQRES records:

>d2b4ja_ c.55.3.2 (A:) Retroviral integrase, catalytic domain {Human immunodeficiency virus type 1 [TaxId: 11676]}
cspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftsttvkaacwwagikqefgipynpqsqgviesmnkelkkiigqvrdqaehlkta
vqmavfihnkkrkggiggysagerivdiiatdi

Sequence, based on observed residues (ATOM records):

>d2b4ja_ c.55.3.2 (A:) Retroviral integrase, catalytic domain {Human immunodeficiency virus type 1 [TaxId: 11676]}
cspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftsttvkaacwwagikqefviesmnkelkkiigqvrdqaehlktavqmavfihnk
ksagerivdiiatdi

Timeline for d2b4ja_:

• d2b4ja_ first appeared in SCOP 1.73, called d2b4ja1
  
• d2b4ja_ appears in SCOPe 2.07