Lineage for d2b2tb2 (2b2t B:109-185)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2782725Fold b.34: SH3-like barrel [50036] (21 superfamilies)
    barrel, partly opened; n*=4, S*=8; meander
    the last strand is interrupted by a turn of 3-10 helix
  4. 2785033Superfamily b.34.13: Chromo domain-like [54160] (4 families) (S)
    SH3-like barrel is capped by a C-terminal helix
  5. 2785079Family b.34.13.2: Chromo domain [54165] (8 proteins)
    lacks the SH3-like barrel first strand that can be complemented by bound peptide ligand; in shadow chromo domain the corresponding site is altered by insertion; similarity to the IL8-like fold
  6. 2785080Protein ATP-dependent helicase CHD1 (Chromo domain protein 1) [141220] (2 species)
  7. 2785084Species Human (Homo sapiens) [TaxId:9606] [141221] (5 PDB entries)
    Uniprot O14646 269-366! Uniprot O14646 270-355! Uniprot O14646 366-445! Uniprot O14646 367-443! Uniprot O14646 367-445
  8. 2785098Domain d2b2tb2: 2b2t B:109-185 [127731]
    Other proteins in same PDB: d2b2ta3, d2b2tb3
    automatically matched to 2B2T A:109-186

Details for d2b2tb2

PDB Entry: 2b2t (more details), 2.45 Å

PDB Description: tandem chromodomains of human chd1 complexed with histone h3 tail containing trimethyllysine 4 and phosphothreonine 3
PDB Compounds: (B:) Chromodomain-helicase-DNA-binding protein 1

SCOPe Domain Sequences for d2b2tb2:

Sequence, based on SEQRES records: (download)

>d2b2tb2 b.34.13.2 (B:109-185) ATP-dependent helicase CHD1 (Chromo domain protein 1) {Human (Homo sapiens) [TaxId: 9606]}
spedveyyncqqeltddlhkqyqivgriiahsnqksaagypdyyckwqglpysecswedg
aliskkfqamideyfsr

Sequence, based on observed residues (ATOM records): (download)

>d2b2tb2 b.34.13.2 (B:109-185) ATP-dependent helicase CHD1 (Chromo domain protein 1) {Human (Homo sapiens) [TaxId: 9606]}
spedveyyncqqeltddlhkqyqivgriiahsnqksgypdyyckwqglpysecswedgal
iskkfqamideyfsr

SCOPe Domain Coordinates for d2b2tb2:

Click to download the PDB-style file with coordinates for d2b2tb2.
(The format of our PDB-style files is described here.)

Timeline for d2b2tb2: