Lineage for d2b1ah1 (2b1a H:1-113)

  1. Root: SCOPe 2.03
  2. 1287432Class b: All beta proteins [48724] (174 folds)
  3. 1287433Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1287434Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1287435Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 1287638Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 1287642Species Engineered (including hybrid species) [88562] (68 PDB entries)
    SQ NA # humanized antidoby; bactericidal Fab-h6831 ! SQ NA # humanized antibody ! SQ NA # Humanized antibody ! SQ NA # engineered antibody
  8. 1287677Domain d2b1ah1: 2b1a H:1-113 [127662]
    Other proteins in same PDB: d2b1ah2
    automatically matched to d1fgvh_

Details for d2b1ah1

PDB Entry: 2b1a (more details), 2.35 Å

PDB Description: crystal structure analysis of anti-hiv-1 v3 fab 2219 in complex with ug1033 peptide
PDB Compounds: (H:) Fab 2219, heavy chain

SCOPe Domain Sequences for d2b1ah1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2b1ah1 b.1.1.1 (H:1-113) Immunoglobulin heavy chain variable domain, VH {Engineered (including hybrid species)}

SCOPe Domain Coordinates for d2b1ah1:

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Timeline for d2b1ah1: