Lineage for d2az5c1 (2az5 C:10-157)

  1. Root: SCOP 1.73
  2. 651986Class b: All beta proteins [48724] (165 folds)
  3. 662724Fold b.22: TNF-like [49841] (1 superfamily)
    sandwich, 10 strands in 2 sheets; jelly-roll
  4. 662725Superfamily b.22.1: TNF-like [49842] (1 family) (S)
  5. 662726Family b.22.1.1: TNF-like [49843] (13 proteins)
  6. 662868Protein Tumor necrosis factor (TNF) [49848] (2 species)
  7. 662869Species Human (Homo sapiens) [TaxId:9606] [49849] (7 PDB entries)
  8. 662873Domain d2az5c1: 2az5 C:10-157 [127601]
    automatically matched to d1tnfa_
    complexed with 307

Details for d2az5c1

PDB Entry: 2az5 (more details), 2.1 Å

PDB Description: crystal structure of tnf-alpha with a small molecule inhibitor
PDB Compounds: (C:) Tumor necrosis factor (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) (Cachectin) [Contains: Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form]

SCOP Domain Sequences for d2az5c1:

Sequence, based on SEQRES records: (download)

>d2az5c1 b.22.1.1 (C:10-157) Tumor necrosis factor (TNF) {Human (Homo sapiens) [TaxId: 9606]}
dkpvahvvanpqaegqlqwlnrranallangvelrdnqlvvpseglyliysqvlfkgqgc
psthvllthtisriavsyqtkvnllsaikspcqretpegaeakpwyepiylggvfqlekg
drlsaeinrpdyldfaesgqvyfgiial

Sequence, based on observed residues (ATOM records): (download)

>d2az5c1 b.22.1.1 (C:10-157) Tumor necrosis factor (TNF) {Human (Homo sapiens) [TaxId: 9606]}
dkpvahvvanpqaegqlqwlnllangvelrdnqlvvpseglyliysqvlfkgqgcpsthv
llthtisriavtkvnllsaikspcpwyepiylggvfqlekgdrlsaeinrpdyldfaesg
qvyfgiial

SCOP Domain Coordinates for d2az5c1:

Click to download the PDB-style file with coordinates for d2az5c1.
(The format of our PDB-style files is described here.)

Timeline for d2az5c1: