SCOPe 2.08: Domain d2axaa_: 2axa A:

Lineage for d2axaa_ (2axa A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Androgen receptor [63621] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63623] (65 PDB entries)
   Uniprot P10275 671-919

8. Domain d2axaa_: 2axa A: [127482]
   automated match to d1e3ga_
   complexed with fhm

Details for d2axaa_

PDB Entry: 2axa, 1.8 Å

PDB Description: crystal structure of the androgen receptor ligand binding domain in complex with s-1

PDB Compounds: (A:) Androgen receptor

SCOPe Domain Sequences for d2axaa_:

Sequence, based on SEQRES records:

>d2axaa_ a.123.1.1 (A:) Androgen receptor {Human (Homo sapiens) [TaxId: 9606]}
iflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhvd
dqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrhls
qefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrknpts
csrrfyqltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkilsgkv
kpiyfh

Sequence, based on observed residues (ATOM records):

>d2axaa_ a.123.1.1 (A:) Androgen receptor {Human (Homo sapiens) [TaxId: 9606]}
iflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhvd
dqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrhls
qefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiacsrrfyql
tklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkilsgkvkpiyfh

Timeline for d2axaa_:

• d2axaa_ first appeared in SCOP 1.73, called d2axaa1
  
• d2axaa_ appears in SCOPe 2.07