SCOP 1.75: Domain d2ax6a1: 2ax6 A:672-917

Lineage for d2ax6a1 (2ax6 A:672-917)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (33 proteins)

6. Protein Androgen receptor [63621] (3 species)

7. Species Rat (Rattus norvegicus) [TaxId:10116] [63622] (7 PDB entries)

8. Domain d2ax6a1: 2ax6 A:672-917 [127479]
   automatically matched to d1i38a_
   complexed with hft; mutant

Details for d2ax6a1

PDB Entry: 2ax6, 1.5 Å

PDB Description: crystal structure of the androgen receptor ligand binding domain t877a mutant in complex with hydroxyflutamide

PDB Compounds: (A:) Androgen receptor

SCOP Domain Sequences for d2ax6a1:

Sequence, based on SEQRES records:

>d2ax6a1 a.123.1.1 (A:672-917) Androgen receptor {Rat (Rattus norvegicus) [TaxId: 10116]}
iflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhvd
dqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrhls
qefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrknpts
csrrfyqltklldsvqpiarelhqfafdllikshmvsvdfpemmaeiisvqvpkilsgkv
kpiyfh

Sequence, based on observed residues (ATOM records):

>d2ax6a1 a.123.1.1 (A:672-917) Androgen receptor {Rat (Rattus norvegicus) [TaxId: 10116]}
iflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhvd
dqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrhls
qefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiaptscsrrf
yqltklldsvqpiarelhqfafdllikshmvsvdfpemmaeiisvqvpkilsgkvkpiyf
h

Timeline for d2ax6a1:

• d2ax6a1 first appeared in SCOP 1.73
  
• d2ax6a1 is called d2ax6a_ in SCOPe 2.01
  
• d2ax6a1 appears in the current release, SCOPe 2.08, called d2ax6a_