SCOPe 2.05: Domain d2awha_: 2awh A:

Lineage for d2awha_ (2awh A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator-activated receptor delta, PPAR-DELTA [48526] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48527] (16 PDB entries)

8. Domain d2awha_: 2awh A: [127433]
   automated match to d1gwxa_
   complexed with b7g, vca

Details for d2awha_

PDB Entry: 2awh, 2 Å

PDB Description: human nuclear receptor-ligand complex 1

PDB Compounds: (A:) Peroxisome proliferator activated receptor delta

SCOPe Domain Sequences for d2awha_:

Sequence, based on SEQRES records:

>d2awha_ a.123.1.1 (A:) Peroxisome proliferator-activated receptor delta, PPAR-DELTA {Human (Homo sapiens) [TaxId: 9606]}
dlkafskhiynaylknfnmtkkkarsiltgkashtapfvihdietlwqaekglvwkqlvn
glppykeisvhvfyrcqcttvetvreltefaksipsfsslflndqvtllkygvheaifam
lasivnkdgllvangsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdlalfia
aiilcgdrpglmnvprveaiqdtilralefhlqanhpdaqqlfpkllqkmadlrqlvteh
aqmmqrikktetetslhpllqeiykdmy

Sequence, based on observed residues (ATOM records):

>d2awha_ a.123.1.1 (A:) Peroxisome proliferator-activated receptor delta, PPAR-DELTA {Human (Homo sapiens) [TaxId: 9606]}
dlkafskhiynaylknfnmtkkkarsilthtapfvihdietlwqaekglvwkeisvhvfy
rcqcttvetvreltefaksipsfsslflndqvtllkygvheaifamlasivnkdgllvan
gsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdlalfiaaiilcgdrpglmnv
prveaiqdtilralefhlqanhpdaqqlfpkllqkmadlrqlvtehaqmmqrikktetet
slhpllqeiykdmy

Timeline for d2awha_:

• d2awha_ first appeared in SCOP 1.73, called d2awha1
  
• d2awha_ appears in SCOPe 2.04
  
• d2awha_ appears in SCOPe 2.06
  
• d2awha_ appears in the current release, SCOPe 2.08