SCOP 1.73: Domain d2avda1: 2avd A:44-262

Lineage for d2avda1 (2avd A:44-262)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (52 families)

5. Family c.66.1.1: COMT-like [53336] (3 proteins)

6. Protein COMT domain-containing protein 1, COMTD1 [142571] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [142572] (1 PDB entry)

8. Domain d2avda1: 2avd A:44-262 [127377]
   complexed with sam

Details for d2avda1

PDB Entry: 2avd, 1.7 Å

PDB Description: Crystal Structure of Human Catechol-O-methyltransferase domain containing 1

PDB Compounds: (A:) Catechol-O-methyltransferase

SCOP Domain Sequences for d2avda1:

Sequence; same for both SEQRES and ATOM records:

>d2avda1 c.66.1.1 (A:44-262) COMT domain-containing protein 1, COMTD1 {Human (Homo sapiens) [TaxId: 9606]}
qcllppedsrlwqyllsrsmrehpalrslrlltleqpqgdsmmtceqaqllanlarliqa
kkaldlgtftgysalalalalpadgrvvtcevdaqppelgrplwrqaeaehkidlrlkpa
letldellaageagtfdvavvdadkencsayyerclqllrpggilavlrvlwrgkvlqpp
kgdvaaecvrnlnerirrdvrvyisllplgdgltlafki

Timeline for d2avda1:

• d2avda1 is new in SCOP 1.73
  
• d2avda1 appears in SCOP 1.75
  
• d2avda1 appears in the current release, SCOPe 2.08