SCOPe 2.08: Domain d2arva_: 2arv A:

Lineage for d2arva_ (2arv A:)

1. Root: SCOPe 2.08

2. Class g: Small proteins [56992] (100 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families)

5. Family g.17.1.2: Transforming growth factor (TGF)-beta [57507] (8 proteins)

6. Protein Activin A (Inhibin beta A) [90170] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [90171] (10 PDB entries)
   Uniprot P08476 311-426

8. Domain d2arva_: 2arv A: [127218]
   automated match to d1s4yb_
   complexed with 1pg, gol, so4

Details for d2arva_

PDB Entry: 2arv, 2 Å

PDB Description: Structure of human Activin A

PDB Compounds: (A:) Inhibin beta A chain

SCOPe Domain Sequences for d2arva_:

Sequence; same for both SEQRES and ATOM records:

>d2arva_ g.17.1.2 (A:) Activin A (Inhibin beta A) {Human (Homo sapiens) [TaxId: 9606]}
glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

Timeline for d2arva_:

• d2arva_ first appeared in SCOP 1.73, called d2arva1
  
• d2arva_ appears in SCOPe 2.07