SCOPe 2.06: Domain d2aq0a_: 2aq0 A:

Lineage for d2aq0a_ (2aq0 A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.60: SAM domain-like [47768] (16 superfamilies)
   4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins

4. Superfamily a.60.2: RuvA domain 2-like [47781] (7 families)
   duplication: contains two helix-hairpin-helix (HhH) motifs

5. Family a.60.2.5: Hef domain-like [140629] (4 proteins)
   helicase/nuclease domain; forms homo and heterodimers; probably includes the Excinuclease UvrC C-terminal domain ((81795), that contains a single NMR structure of a monomeric truncated domain, 1kft)

6. Protein DNA repair endonuclease XPF [140634] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [140636] (4 PDB entries)
   Uniprot Q92889 823-905! Uniprot Q92889 837-898

8. Domain d2aq0a_: 2aq0 A: [127136]
   automated match to d2aq0a1

Details for d2aq0a_

PDB Entry: 2aq0

PDB Description: solution structure of the human homodimeric dna repair protein xpf

PDB Compounds: (A:) DNA repair endonuclease XPF

SCOPe Domain Sequences for d2aq0a_:

Sequence; same for both SEQRES and ATOM records:

>d2aq0a_ a.60.2.5 (A:) DNA repair endonuclease XPF {Human (Homo sapiens) [TaxId: 9606]}
mdsetlpesekynpgpqdfllkmpgvnakncrslmhhvkniaelaalsqdeltsilgnaa
nakqlydfihtsfaevvskgkgkk

Timeline for d2aq0a_:

• d2aq0a_ first appeared in SCOP 1.73, called d2aq0a1
  
• d2aq0a_ appears in SCOPe 2.05
  
• d2aq0a_ appears in SCOPe 2.07
  
• d2aq0a_ appears in the current release, SCOPe 2.08