Lineage for d2aowb1 (2aow B:13-292)

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 704539Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
  4. 704540Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (52 families) (S)
  5. 704856Family c.66.1.19: Histamine methyltransferase [75261] (1 protein)
  6. 704857Protein Histamine methyltransferase [75262] (1 species)
  7. 704858Species Human (Homo sapiens) [TaxId:9606] [75263] (7 PDB entries)
  8. 704870Domain d2aowb1: 2aow B:13-292 [127105]
    automatically matched to d1jqea_
    complexed with tha; mutant

Details for d2aowb1

PDB Entry: 2aow (more details), 2.97 Å

PDB Description: histamine methyltransferase (natural variant i105) complexed with the acetylcholinesterase inhibitor and altzheimer's disease drug tacrine
PDB Compounds: (B:) Histamine N-methyltransferase

SCOP Domain Sequences for d2aowb1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2aowb1 c.66.1.19 (B:13-292) Histamine methyltransferase {Human (Homo sapiens) [TaxId: 9606]}

SCOP Domain Coordinates for d2aowb1:

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Timeline for d2aowb1: