Lineage for d2aowa_ (2aow A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2129295Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
  4. 2129296Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families) (S)
  5. 2129827Family c.66.1.19: Histamine methyltransferase [75261] (1 protein)
  6. 2129828Protein Histamine methyltransferase [75262] (1 species)
  7. 2129829Species Human (Homo sapiens) [TaxId:9606] [75263] (7 PDB entries)
  8. 2129840Domain d2aowa_: 2aow A: [127104]
    automated match to d1jqda_
    complexed with tha

Details for d2aowa_

PDB Entry: 2aow (more details), 2.97 Å

PDB Description: Histamine Methyltransferase (Natural Variant I105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine
PDB Compounds: (A:) Histamine N-methyltransferase

SCOPe Domain Sequences for d2aowa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2aowa_ c.66.1.19 (A:) Histamine methyltransferase {Human (Homo sapiens) [TaxId: 9606]}
mrslfsdhgkyvesfrrflnhstehqcmqefmdkklpgiigrigdtkseikilsigggag
eidlqilskvqaqypgvcinnevvepsaeqiakykelvakisnlenvkfawhketsseyq
srmlekkelqkwdfihmiqmlyyvkdipatlkffhsllgtnakmliivvsgssgwdklwk
kygsrfpqddlcqyitsddltqmldnlglkyecydllstmdisdcfidgnengdllwdfl
tetcnfnatappdlraelgkdlqepefsakkegkvlfnntlsfiviea

SCOPe Domain Coordinates for d2aowa_:

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(The format of our PDB-style files is described here.)

Timeline for d2aowa_: